产品货号：
Z12746
中文名称：
CD42b/GP1BA抗体
英文名称：
Anti-CD42b/GP1BA Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD42b/GP1BA Antibody |
| 指标别名 | BSS;CD42b;CD42b alpha;GP1B;GP1BA |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | GP1BA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from the Internal region of human CD42b. |
| 计算分子量 | 72KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | Immunogen affinity purified |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Platelet glycoprotein Ib alpha chain also known as glycoprotein Ib (platelet),alpha polypeptide or CD42b (Cluster of Differentiation 42b),is a protein that in humans is encoded by the GP1BA gene.Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer,an alpha chain and a beta chain,that is linked by disulfide bonds.The Gp Ib functions as a receptor for von Willebrand factor (VWF).The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V.The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury,and also initiates signaling events within the platelet that lead to enhanced platelet activation,thrombosis,and hemostasis.This gene encodes the alpha subunit.Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease.The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. |
| Uniprot ID | P07359 |
| 基因名全称 | Platelet glycoprotein Ib alpha chain |
| 推荐稀释比 | WB,1:500～1:2000 IHC-P,1:100～1:300 |
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